Patients come into my office confused by commercials on TV for expensive new drugs for diseases with unfamiliar acronyms. It takes several valuable minutes to respond and get back on track with the treatment plan. What has been accomplished in medicine with the blitz of pharmaceutical ads over the past few decades? The U.S. pharmaceutical industry spent $7.6 billion on product claim direct-to-consumer advertising (DTCA) in 2022, up from $6.8 billion in 2021, with $1.68 billion of that for just ten drugs.