Excessive DNA Contamination in mRNA Vaccines Presents “Substantial Risk” of Cancer, Say 52 Scientists and Academics

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by Rebekah Barnett’, Daily Sceptic:

The Australian Government should immediately suspend the use of Pfizer and Moderna Covid vaccines due to accumulating evidence of high levels of synthetic DNA contamination in the shots, which present a “substantial risk” of genomic integration and long-term health impacts, including cancers, say leading scientists and academics.

In a letter to Prime Minister Anthony Albanese, Russell Broadbent, independent MP for the federal seat of Monash, said that “immediate action through a suspension of these products is critical to mitigate further risk”, after independent testing of Australian vials of modified RNA (mod-RNA) Covid vaccines detected residual synthetic DNA at levels up to 145 above the legal limit.

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The letter, circulated to all Australian MPs and Senators, is co-signed by 52 scientists and academics, many at the top of their fields, including Professor of Oncology Angus Dalgleish, Emeritus Professor Wendy Hoy, an expert in chronic disease, Emeritus Professor Robert Clancy, an immunologist who developed a bronchitis vaccine, geneticist Professor Alexandra Henrion Caude and microbiologist Professor Sucharit Bhakdi MD.

An accompanying science summary describes the concerns of Broadbent and co-signatories, who are asking the PM to adopt a “precautionary approach”, with the recommendation that “the Minister for Agriculture initiate a Biosecurity Import Risk Analysis of these products, potentially leading to the suspension of these products due to the risks they pose to human health”.

“Excessive synthetic foreign DNA encapsulated in lipid nanoparticles can integrate into human cells, potentially leading to genomic instability, cancers, immune system disruption and adverse hereditary effects,” explains the summary, which details the results of independent testing of the vaccines to date.

Residual synthetic DNA, a byproduct from the mod-RNA vaccine manufacturing process, is allowed under TGA regulations in levels of up to 10 nanograms (ng) per vaccine dose, a regulatory limit that was set for traditional vaccines and was not amended for mod-RNA products using lipid nanoparticles (LNPs).

The summary goes on to explain why the LNP packaging of residual synthetic DNA makes these products different to traditional vaccines that may contain “naked” residual DNA.

“Crucially, naked DNA has no ability to cross cell membranes and enter cells. In contrast, synthetic DNA encapsulated in LNPs possesses a high transfection efficiency, meaning, the LNP-modDNA complexes are efficient at delivering synthetic DNA into human cells,” the summary states.

The summary cites research indicating that the presence of foreign DNA within the cell alone can induce cancer, but the risk is increased if the DNA enters the cell nucleus. This can occur in dividing cells, and the presence of an SV40 enhancer sequence (in Pfizer only), which is “long known to assist entry into the nucleus, even when cells are not undergoing cell division”, increases the risk further.

Once synthetic DNA is inside the cell nucleus, genomic integration is possible, the summary explains. And, “when genomic integration of foreign DNA occurs at the wrong place within the genome, it frequently induces malignant diseases, cancers, especially leukaemia”.

Genomic integration and cancer formation arising from synthetic DNA contamination are yet to be proven in vivo (in human tissue). However, the summary lists 19 resources from the scientific literature justifying the stated concerns and calls for a full and thorough investigation. Additionally, the summary cites putative evidence of genomic integration of residual synthetic DNA from the Pfizer vaccine in cancer cell lines.

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