by Robert Kogon, Daily Sceptic:
Prior to the advent of COVID-19, BioNTech, the German developer and owner of the so-called ‘Pfizer’ vaccine, had only ever done trials for cancer therapies. This was the company’s focus, not infectious diseases. But none of those trials got very far. None of BioNTech’s experimental cancer drugs had ever made it to a large-scale phase 3 clinical trial, and one of the just three phase 2 trials registered by BioNTech prior to 2020 was “prematurely ended” for unknown reasons. All in all, BioNTech had only tested its drugs on just over 400 – for the most part, extremely-ill – cancer patients.
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In light of reports of surging cancer diagnoses since the rollout of the mRNA-based Covid vaccines, I wondered in a recent article whether BioNTech’s trials faltered because its mRNA-based cancer therapies were in fact promoting cancerous growths rather than inhibiting or reversing them.
Well, now we have further support for this hypothesis.
A new preprint by Rubio-Casillas et al. in the International Journal of Biological Macromolecules asks ‘N1-methyl-pseudouridine (m1Ψ): Friend or foe of cancer?‘ Substituting N1-methyl-pseudouridine for naturally occurring uridine is precisely the innovation at the heart of BioNTech’s mRNA platform, which is thus, in reality, a modRNA or modified RNA platform. Katalin Karikó, who would go on to become a BioNTech Vice-President, shared the Nobel Prize in Medicine with Drew Weissman for having discovered this innovation.
N1-methyl-pseudouridine: friend or foe of cancer? The authors’ answer is clear: friend… of cancer. Thus, the abstract reads (emphasis added):
Additionally, it has been discovered that the mRNA vaccines inhibit essential immunological pathways, thus impairing early interferon signaling. … Evidence is provided that adding 100 % of N1-methyl-pseudouridine (m1Ψ) to the mRNA vaccine in a melanoma model stimulated cancer growth and metastasis, while non-modified mRNA vaccines induced opposite results, thus suggesting that COVID-19 mRNA vaccines could aid cancer development.
Did BioNTech and the regulatory authority already know what Rubio-Casillas et al. found out? This is to say: did they know that the company’s mRNA platform could be oncogenic before the platform was rolled out to literally billions of people around the world as the basis of its COVID-19 vaccine?
The competent regulatory authority for two of the trials, including the one that was “prematurely ended”, was none other than the PEI: Germany’s vaccines and medicines regulator, whose cozy relationship with BioNTech I have written about here. (The competent authority for the third trial was Germany’s Federal Institute for Drugs and Medical Devices (BfArM), a sister organisation of the PEI.)
As noted in my previous article on the subject, thanks to an American FOIA request and a court order, we have a virtually complete record of the clinical trials of BioNTech’s COVID-19 vaccine. These are the ‘Pfizer documents’ – a misnomer, since Pfizer merely conducted the trials on the German company’s behalf – which the FDA famously wanted to keep hidden for some 75 years.
